BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Center for Biomedical Research Excellence (COBRE) - ECPv6.15.17.1//NONSGML v1.0//EN CALSCALE:GREGORIAN METHOD:PUBLISH X-WR-CALNAME:Center for Biomedical Research Excellence (COBRE) X-ORIGINAL-URL:/cobre X-WR-CALDESC:Events for Center for Biomedical Research Excellence (COBRE) REFRESH-INTERVAL;VALUE=DURATION:PT1H X-Robots-Tag:noindex X-PUBLISHED-TTL:PT1H BEGIN:VTIMEZONE TZID:America/New_York BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20250309T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20251102T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20260308T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20261101T060000 END:STANDARD BEGIN:DAYLIGHT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT DTSTART:20270314T070000 END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0400 TZOFFSETTO:-0500 TZNAME:EST DTSTART:20271107T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT DTSTART;TZID=America/New_York:20260403T150000 DTEND;TZID=America/New_York:20260403T163000 DTSTAMP:20260520T025913 CREATED:20260331T180058Z LAST-MODIFIED:20260331T180058Z UID:10000040-1775228400-1775233800@umaine.edu SUMMARY:Exploring tissue-specific mechanisms and requirements for nucleolar organization using C. elegans DESCRIPTION:The School of Biology and Ecology presents: \nExploring tissue-specific mechanisms and requirements for nucleolar organization using C. elegans \nSpeaker:  Dr. Emily Spaulding Assistant Professor and The George Wojtech Endowed Chair in Neurobiology at MDI Biological Lab \nFriday\, April 3\, 3pm Norman Smith 107 \nRefreshments served! \nDisruptions in the organization of neurons contributes to neurodegeneration\, including Alzheimer’s disease\, Parkinson’s disease\, and ALS. However\, studying neuronal organization in mammals is technically challenging because neurons are buried deep inside the animal. To overcome this challenge\, the Spaulding Lab uses the optically clear nematode\, C.elegans\, which contains 302 well characterized neurons that are visible in an intact\, living animal. Her lab combines genetic engineering of neurodegenerative disease-associated genes with super-resolution imaging of living\, adult worms to understand how disrupted cell organization leads to neuronal dysfunction. Their goal is to uncover new therapeutic targets to treat neurodegenerative disease. URL:/cobre/event/exploring-tissue-specific-mechanisms-and-requirements-for-nucleolar-organization-using-c-elegans/ LOCATION:Norman Smith Hall 107 ATTACH;FMTTYPE=image/png:/cobre/wp-content/uploads/sites/681/2026/03/SpauldingSeminarPoster-scaled-e1774979777360.png END:VEVENT END:VCALENDAR