{"id":1171,"date":"2025-06-27T10:48:59","date_gmt":"2025-06-27T14:48:59","guid":{"rendered":"https:\/\/umaine.edu\/compumaine\/?page_id=1171"},"modified":"2025-06-27T10:48:59","modified_gmt":"2025-06-27T14:48:59","slug":"projects-2","status":"publish","type":"page","link":"https:\/\/umaine.edu\/compumaine\/projects-2\/","title":{"rendered":"Projects"},"content":{"rendered":"<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_51704f-87{margin-top:0px;margin-bottom:0px;}.kb-row-layout-id1171_51704f-87 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_51704f-87 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_51704f-87 > .kt-row-column-wrap{column-gap:60px;row-gap:var(--global-kb-gap-md, 2rem);max-width:1268px;padding-top:50px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_51704f-87{background-image:linear-gradient(60deg,rgb(8,46,88) 47%,rgb(65,118,161) 93%);}.kb-row-layout-id1171_51704f-87 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_51704f-87 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-sm, 1rem);grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_51704f-87 > .kt-row-column-wrap{padding-top:0px;padding-right:0px;padding-bottom:25px;padding-left:0px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_51704f-87 alignfull kt-row-has-bg um-UMBHFullHomepageTemplate2 wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top kb-theme-content-width\">\n<style>.kadence-column1171_becd51-82 > .kt-inside-inner-col,.kadence-column1171_becd51-82 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_becd51-82 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_becd51-82 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_becd51-82 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_becd51-82 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_becd51-82{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_becd51-82 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_becd51-82 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_becd51-82\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3, .wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3[data-kb-block=\"kb-adv-heading1171_c54d91-c3\"]{padding-top:0px;padding-bottom:0px;text-align:center;font-size:45px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3[data-kb-block=\"kb-adv-heading1171_c54d91-c3\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3[data-kb-block=\"kb-adv-heading1171_c54d91-c3\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3, .wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3[data-kb-block=\"kb-adv-heading1171_c54d91-c3\"]{text-align:center!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3, .wp-block-kadence-advancedheading.kt-adv-heading1171_c54d91-c3[data-kb-block=\"kb-adv-heading1171_c54d91-c3\"]{padding-right:25px;padding-left:25px;text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_c54d91-c3 wp-block-kadence-advancedheading has-white-color has-text-color\" data-kb-block=\"kb-adv-heading1171_c54d91-c3\">projects at compumaine<\/h2>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12, .wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12[data-kb-block=\"kb-adv-heading1171_b03715-12\"]{padding-right:135px;padding-left:135px;margin-top:0px;text-align:center;font-size:20px;line-height:32px;font-weight:400;font-style:normal;font-family:Fraunces;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12[data-kb-block=\"kb-adv-heading1171_b03715-12\"] mark.kt-highlight{font-size:20px;line-height:32px;font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12[data-kb-block=\"kb-adv-heading1171_b03715-12\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12, .wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12[data-kb-block=\"kb-adv-heading1171_b03715-12\"]{padding-right:75px;padding-left:75px;text-align:center!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12, .wp-block-kadence-advancedheading.kt-adv-heading1171_b03715-12[data-kb-block=\"kb-adv-heading1171_b03715-12\"]{padding-right:25px;padding-left:25px;margin-right:0px;margin-left:0px;font-size:18px;text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_b03715-12 wp-block-kadence-advancedheading has-white-color has-text-color\" data-kb-block=\"kb-adv-heading1171_b03715-12\" data-aos-duration=\"1200\" data-aos-once=\"true\"><\/p>\n<\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_91f5c2-6d > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_91f5c2-6d > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_91f5c2-6d > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_91f5c2-6d{background-color:#e5f0f9;}.kb-row-layout-id1171_91f5c2-6d > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_91f5c2-6d > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_91f5c2-6d > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_91f5c2-6d alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_b4ef43-1e > .kt-inside-inner-col,.kadence-column1171_b4ef43-1e > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_b4ef43-1e > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_b4ef43-1e > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_b4ef43-1e > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_b4ef43-1e > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_b4ef43-1e{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_b4ef43-1e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_b4ef43-1e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_b4ef43-1e\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_52fea7-a1 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_52fea7-a1 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_52fea7-a1 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_52fea7-a1 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_52fea7-a1 > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_52fea7-a1 > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_52fea7-a1 alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_a1f956-4f > .kt-inside-inner-col,.kadence-column1171_a1f956-4f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_a1f956-4f > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_a1f956-4f > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_a1f956-4f > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_a1f956-4f > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_a1f956-4f{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_a1f956-4f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_a1f956-4f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_a1f956-4f\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b, .wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b[data-kb-block=\"kb-adv-heading1171_6d942e-2b\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b[data-kb-block=\"kb-adv-heading1171_6d942e-2b\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b[data-kb-block=\"kb-adv-heading1171_6d942e-2b\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b, .wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b[data-kb-block=\"kb-adv-heading1171_6d942e-2b\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b, .wp-block-kadence-advancedheading.kt-adv-heading1171_6d942e-2b[data-kb-block=\"kb-adv-heading1171_6d942e-2b\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_6d942e-2b wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_6d942e-2b\">microenvironment disruption in tumorous breasts<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"282\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image.png\" alt=\"\" class=\"wp-image-849\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image.png 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image-300x110.png 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image-105x39.png 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image-317x116.png 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image-423x155.png 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/image-634x233.png 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_01d275-17{margin-top:-5px;}.kb-row-layout-id1171_01d275-17 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_01d275-17 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_01d275-17 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_01d275-17 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_01d275-17 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_01d275-17 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_01d275-17 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col,.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_30d5d5-e4{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_30d5d5-e4 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_30d5d5-e4\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27, .wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27[data-kb-block=\"kb-adv-heading1171_4ae388-27\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27[data-kb-block=\"kb-adv-heading1171_4ae388-27\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27[data-kb-block=\"kb-adv-heading1171_4ae388-27\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27, .wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27[data-kb-block=\"kb-adv-heading1171_4ae388-27\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27, .wp-block-kadence-advancedheading.kt-adv-heading1171_4ae388-27[data-kb-block=\"kb-adv-heading1171_4ae388-27\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_4ae388-27 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_4ae388-27\">We successfully demonstrated preliminary evidence that tissue disruption and loss of homeostasis in breast tissue microenvironment and breast bilateral asymmetry can be quantitatively and objectively assessed from mammography via a localized, wavelet-based analysis of the whole breast. The WTMM method was used to quantify density fluctuations from mammographic breast tissue via the Hurst exponent (H). Each entire mammogram was cut in thousands of 360\u00d7360 pixel sub-regions in a gridding scheme of overlapping sliding windows, with each window boundary separated by 32 pixels. The WTMM method was applied to each sub-region individually. The density fluctuations in healthy mammographic breast tissue are either monofractal anti-correlated (H&lt;1\/2) for fatty tissue or monofractal long-range correlated (H&gt;1\/2) for dense tissue. However, tissue regions with H~1\/2, as well as left vs. right breast asymmetries, were found preferably in tumorous (benign or cancer) breasts vs. normal breasts, as quantified via a combination metric yielding a p-value ~ 0.0006.<\/p>\n\n\n<style>.kb-row-layout-id1171_b74d35-5f > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_b74d35-5f > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_b74d35-5f > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_b74d35-5f > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_b74d35-5f > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_b74d35-5f > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_b74d35-5f alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_81fd0a-57 > .kt-inside-inner-col,.kadence-column1171_81fd0a-57 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_81fd0a-57 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_81fd0a-57 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_81fd0a-57 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_81fd0a-57 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_81fd0a-57{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_81fd0a-57 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_81fd0a-57 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_81fd0a-57\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_e95258-5e .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_e95258-5e .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_e95258-5e .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e95258-5e:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_e95258-5e .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_e95258-5e .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_e95258-5e .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e95258-5e .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_e95258-5e .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e95258-5e > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_e95258-5e kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_b5c99c-9e\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Marin, Z., Batchelder, K. A., Toner, B. C., Guimond, L., Gerasimova-Chechkina, E., Harrow, A. R., Arneodo, A. and Khalil, A. 2017 Mammographic evidence of microenvironment changes in tumorous breasts. Medical Physics, 44: 1324-1336.&nbsp;<a href=\"https:\/\/doi.org\/10.1002\/mp.12120\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/mp.12120<\/a><\/li>\n\n\n\n<li>Gerasimova-Chechkina, E, Toner, B, Marin, Z, Audit, B, Roux, SG, Argoul, F, Khalil, A, Gileva, O, Naimark, O, Arneodo, A 2016 Comparative multifractal analysis of dynamic infrared thermograms and X-ray mammograms enlightens changes in the environment of malignant tumors, Frontiers in Physiology, 7, 336 (15 pages).&nbsp;<a href=\"https:\/\/doi.org\/10.3389\/fphys.2016.00336\">https:\/\/doi.org\/10.3389\/fphys.2016.00336<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_4f50d1-7d > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_4f50d1-7d > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_4f50d1-7d > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_4f50d1-7d{background-image:linear-gradient(135deg,rgb(8,46,88) 0%,rgb(65,118,161) 99%);}.kb-row-layout-id1171_4f50d1-7d > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_4f50d1-7d > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_4f50d1-7d > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_4f50d1-7d alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_311d6e-d2 > .kt-inside-inner-col,.kadence-column1171_311d6e-d2 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_311d6e-d2 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_311d6e-d2 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_311d6e-d2 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_311d6e-d2 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_311d6e-d2{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_311d6e-d2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_311d6e-d2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_311d6e-d2\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_4b5e4c-1e > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_4b5e4c-1e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_4b5e4c-1e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_4b5e4c-1e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_4b5e4c-1e > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_4b5e4c-1e > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_4b5e4c-1e alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_f75407-68 > .kt-inside-inner-col,.kadence-column1171_f75407-68 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_f75407-68 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_f75407-68 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_f75407-68 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_f75407-68 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_f75407-68{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_f75407-68 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_f75407-68 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_f75407-68\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42, .wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42[data-kb-block=\"kb-adv-heading1171_1aa390-42\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42[data-kb-block=\"kb-adv-heading1171_1aa390-42\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42[data-kb-block=\"kb-adv-heading1171_1aa390-42\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42, .wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42[data-kb-block=\"kb-adv-heading1171_1aa390-42\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42, .wp-block-kadence-advancedheading.kt-adv-heading1171_1aa390-42[data-kb-block=\"kb-adv-heading1171_1aa390-42\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_1aa390-42 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_1aa390-42\">fractal characterization of microcalcification clusters from mammography<\/h2>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_e4e2d9-65{margin-top:-5px;}.kb-row-layout-id1171_e4e2d9-65 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_e4e2d9-65 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_e4e2d9-65 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_e4e2d9-65 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_e4e2d9-65 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_e4e2d9-65 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_e4e2d9-65 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_a45207-9b > .kt-inside-inner-col,.kadence-column1171_a45207-9b > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_a45207-9b > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_a45207-9b > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_a45207-9b > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_a45207-9b > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_a45207-9b{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_a45207-9b > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_a45207-9b > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_a45207-9b\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad, .wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad[data-kb-block=\"kb-adv-heading1171_811b4c-ad\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad[data-kb-block=\"kb-adv-heading1171_811b4c-ad\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_811b4c-ad[data-kb-block=\"kb-adv-heading1171_811b4c-ad\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading1171_811b4c-ad wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_811b4c-ad\">The fractal nature of cancer has become a widely accepted concept in recent years. Using a wavelet-based method to detect microcalcifications (MC) in breast tissue seen in mammograms we have characterized the fractal geometry of benign and malignant MC clusters from two separate 2D projected mammographic views of the same breast, i.e. the cranial-caudal (CC) and mediolateral-oblique (MLO) views. Through a Bayesian analysis, we showed that with 95% credibility, the probability that fractal breast lesions are malignant is between 74% and 98%, and the probability that Euclidean breast lesions are benign is between 76% and 96%. This supports the notion that the fractal structure of malignant tumors is more likely associated with an invasive behavior into the surrounding tissue compared to the non-invasive Euclidean structure of benign tumors.<\/p>\n\n\n<style>.kb-image1171_c32c31-a3 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image1171_c32c31-a3 size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"658\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3.png\" alt=\"\" class=\"kb-img wp-image-976\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3.png 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3-300x257.png 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3-105x90.png 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3-317x272.png 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3-423x362.png 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/fractal-dimension-plot-768x658-3-634x543.png 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9, .wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9[data-kb-block=\"kb-adv-heading1171_0f3f89-e9\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9[data-kb-block=\"kb-adv-heading1171_0f3f89-e9\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9[data-kb-block=\"kb-adv-heading1171_0f3f89-e9\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9, .wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9[data-kb-block=\"kb-adv-heading1171_0f3f89-e9\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9, .wp-block-kadence-advancedheading.kt-adv-heading1171_0f3f89-e9[data-kb-block=\"kb-adv-heading1171_0f3f89-e9\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_0f3f89-e9 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_0f3f89-e9\">Fractal dimension obtained from the MLO view as a function of the fractal dimension obtained from the CC view. A polygonal region is outlined, the inside of which is defined as the \u201cfractal zone\u201d while the outside as the \u201cEuclidean zone\u201d. Cancer = red and benign = green.<\/p>\n\n\n<style>.kb-row-layout-id1171_8da249-26 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_8da249-26 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_8da249-26 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_8da249-26 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_8da249-26 > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_8da249-26 > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_8da249-26 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_aa96f0-1f > .kt-inside-inner-col,.kadence-column1171_aa96f0-1f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_aa96f0-1f > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_aa96f0-1f > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_aa96f0-1f > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_aa96f0-1f > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_aa96f0-1f{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_aa96f0-1f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_aa96f0-1f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_aa96f0-1f\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_d920ed-3d .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_d920ed-3d .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_d920ed-3d .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_d920ed-3d:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_d920ed-3d .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_d920ed-3d .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_d920ed-3d .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_d920ed-3d .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_d920ed-3d .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_d920ed-3d > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_d920ed-3d kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_29788b-62\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Batchelder, KA, Tanenbaum, AB, Albert, S, Guimond, L, Kestener, P, Arneodo, A, Khalil, A 2014. Wavelet-based 3D reconstruction of microcalcification clusters from two mammographic views: New Evidence that fractal tumors are malignant and Euclidean tumors are benign, PLoS One, 9 (9) e107580.&nbsp;<a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0107580\">https:\/\/doi.org\/10.1371\/journal.pone.0107580<\/a><\/li>\n\n\n\n<li>Mooers, Kendra 2013. Characterization of Mammographic Breast Lesions And Their Microenvironment: An Application of a Wavelet-Based Multifractal Formalism. MA Thesis. Mathematics. 91爆料.&nbsp;<a href=\"https:\/\/digitalcommons.library.umaine.edu\/etd\/1910\/\">https:\/\/digitalcommons.library.umaine.edu\/etd\/1910\/<\/a><\/li>\n<\/ol>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe, .wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe[data-kb-block=\"kb-adv-heading1171_a32199-fe\"]{font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe[data-kb-block=\"kb-adv-heading1171_a32199-fe\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_a32199-fe[data-kb-block=\"kb-adv-heading1171_a32199-fe\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading1171_a32199-fe wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_a32199-fe\">. <\/p>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_f7c9d3-c2{background-color:#e5f0f9;}.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_f7c9d3-c2 > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_f7c9d3-c2 alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_2255f6-b9 > .kt-inside-inner-col,.kadence-column1171_2255f6-b9 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_2255f6-b9 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_2255f6-b9 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_2255f6-b9 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_2255f6-b9 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_2255f6-b9{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_2255f6-b9 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_2255f6-b9 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_2255f6-b9\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_2e011f-56 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_2e011f-56 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_2e011f-56 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:75px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_2e011f-56 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_2e011f-56 > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_2e011f-56 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_2e011f-56 alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_8d61ad-be > .kt-inside-inner-col,.kadence-column1171_8d61ad-be > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_8d61ad-be > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_8d61ad-be > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_8d61ad-be > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_8d61ad-be > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_8d61ad-be{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_8d61ad-be > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_8d61ad-be > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_8d61ad-be\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f[data-kb-block=\"kb-adv-heading1171_b6459e-4f\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f[data-kb-block=\"kb-adv-heading1171_b6459e-4f\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f[data-kb-block=\"kb-adv-heading1171_b6459e-4f\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f[data-kb-block=\"kb-adv-heading1171_b6459e-4f\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6459e-4f[data-kb-block=\"kb-adv-heading1171_b6459e-4f\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_b6459e-4f wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_b6459e-4f\">simulated microcalcifications in breast tissue<\/h2>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_48bfdc-f2{margin-top:-5px;}.kb-row-layout-id1171_48bfdc-f2 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_48bfdc-f2 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_48bfdc-f2 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_48bfdc-f2 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_48bfdc-f2 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_48bfdc-f2 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_48bfdc-f2 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_be9924-63 > .kt-inside-inner-col,.kadence-column1171_be9924-63 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_be9924-63 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_be9924-63 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_be9924-63 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_be9924-63 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_be9924-63{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_be9924-63 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_be9924-63 > .kt-inside-inner-col{display:flex;flex-direction:column;justify-content:center;align-items:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_be9924-63\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0[data-kb-block=\"kb-adv-heading1171_d19044-e0\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0[data-kb-block=\"kb-adv-heading1171_d19044-e0\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0[data-kb-block=\"kb-adv-heading1171_d19044-e0\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0[data-kb-block=\"kb-adv-heading1171_d19044-e0\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d19044-e0[data-kb-block=\"kb-adv-heading1171_d19044-e0\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_d19044-e0 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_d19044-e0\">CompuMAINE identified that the Hurst exponent,&nbsp;<em>H<\/em>, which quantifies the global roughness of the image density fluctuations, can distinguish between varying tissue densities found in the breast. CompuMAINE software simulated growth of microcalcifications in tissues of varying roughness and analyzed the fractal dimension and morphology of the simulated microcalcifications. This agent-based model showed the effects of tissue structure on microcalcification morphology.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"387\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2.jpg\" alt=\"\" class=\"wp-image-990\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2.jpg 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2-300x151.jpg 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2-105x53.jpg 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2-317x160.jpg 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2-423x213.jpg 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/microcalcification-768x387-2-634x319.jpg 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9, .wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9[data-kb-block=\"kb-adv-heading1171_bd96dc-f9\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9[data-kb-block=\"kb-adv-heading1171_bd96dc-f9\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9[data-kb-block=\"kb-adv-heading1171_bd96dc-f9\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9, .wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9[data-kb-block=\"kb-adv-heading1171_bd96dc-f9\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9, .wp-block-kadence-advancedheading.kt-adv-heading1171_bd96dc-f9[data-kb-block=\"kb-adv-heading1171_bd96dc-f9\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_bd96dc-f9 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_bd96dc-f9\">The left image shows cluster microcalcification in breast tissue, with the right showing simulated cluster microcalcification.<\/p>\n\n\n<style>.kb-row-layout-id1171_e2db16-e8 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_e2db16-e8 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_e2db16-e8 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_e2db16-e8 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_e2db16-e8 > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_e2db16-e8 > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_e2db16-e8 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_2b069b-4f > .kt-inside-inner-col,.kadence-column1171_2b069b-4f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_2b069b-4f > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_2b069b-4f > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_2b069b-4f > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_2b069b-4f > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_2b069b-4f{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_2b069b-4f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_2b069b-4f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_2b069b-4f\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_659308-46 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_659308-46 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_659308-46 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_659308-46 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_659308-46:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_659308-46 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_659308-46 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_659308-46 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_659308-46 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_659308-46 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_659308-46 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_659308-46 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_659308-46 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_da501f-e4\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Plourde, SM, Marin, Z, Smith, ZR, Toner, BC, Batchelder, KA, Khalil, A 2016. Computational growth model of breast microcalcification clusters in simulated mammographic environments. Computers in Biology and Medicine, 76, 7-13.&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/j.compbiomed.2016.06.020\">https:\/\/doi.org\/10.1016\/j.compbiomed.2016.06.020<\/a><\/li>\n\n\n\n<li>Plourde, Shayne 2015. Modeling the Growth of Breast Microcalcifications in Mathematically-Generated Breast Tissue Environments Using an AgentBased Model. Honors Thesis. Mathematics. 91爆料.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_661de8-3a > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_661de8-3a > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_661de8-3a > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_661de8-3a{background-image:linear-gradient(135deg,rgb(8,46,88) 0%,rgb(65,118,161) 99%);}.kb-row-layout-id1171_661de8-3a > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_661de8-3a > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_661de8-3a > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_661de8-3a alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_44c2fc-75 > .kt-inside-inner-col,.kadence-column1171_44c2fc-75 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_44c2fc-75 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_44c2fc-75 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_44c2fc-75 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_44c2fc-75 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_44c2fc-75{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_44c2fc-75 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_44c2fc-75 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_44c2fc-75\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_0183af-8c > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_0183af-8c > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_0183af-8c > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_0183af-8c > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_0183af-8c > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_0183af-8c > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_0183af-8c alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_f17cc5-ce > .kt-inside-inner-col,.kadence-column1171_f17cc5-ce > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_f17cc5-ce > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_f17cc5-ce > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_f17cc5-ce > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_f17cc5-ce > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_f17cc5-ce{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_f17cc5-ce > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_f17cc5-ce > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_f17cc5-ce\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af, .wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af[data-kb-block=\"kb-adv-heading1171_f02f10-af\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af[data-kb-block=\"kb-adv-heading1171_f02f10-af\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af[data-kb-block=\"kb-adv-heading1171_f02f10-af\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af, .wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af[data-kb-block=\"kb-adv-heading1171_f02f10-af\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af, .wp-block-kadence-advancedheading.kt-adv-heading1171_f02f10-af[data-kb-block=\"kb-adv-heading1171_f02f10-af\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_f02f10-af wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_f02f10-af\">characterization of seizure morphology and frequency variation in genetic models of absence epilepsy<\/h2>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_f9dfc9-5e{margin-top:-5px;}.kb-row-layout-id1171_f9dfc9-5e > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_f9dfc9-5e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_f9dfc9-5e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_f9dfc9-5e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_f9dfc9-5e > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_f9dfc9-5e > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_f9dfc9-5e alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_425548-5c > .kt-inside-inner-col,.kadence-column1171_425548-5c > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_425548-5c > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_425548-5c > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_425548-5c > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_425548-5c > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_425548-5c{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_425548-5c > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_425548-5c > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_425548-5c\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34, .wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34[data-kb-block=\"kb-adv-heading1171_3b6b2b-34\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34[data-kb-block=\"kb-adv-heading1171_3b6b2b-34\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_3b6b2b-34[data-kb-block=\"kb-adv-heading1171_3b6b2b-34\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading1171_3b6b2b-34 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_3b6b2b-34\">Nearly a third of people diagnosed with epilepsy do not respond to current anti-seizure medications, and those who respond often suffer from drug-related side effects. CompuMAINE scientists developed a computational tool to detect spike-wave discharges (SWDs), an indicator of absence seizures. Wavelet-based analysis of electroencephalogram (EEG) signals revealed unusual harmonic patterns in the power spectra of EEG absence seizure signals. These unique characteristics were used to automatically detect SWDs.<\/p>\n\n\n<style>.kb-image1171_9ec7ad-10 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image1171_9ec7ad-10\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"571\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2.jpg\" alt=\"\" class=\"kb-img wp-image-1025\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2.jpg 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2-300x223.jpg 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2-105x78.jpg 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2-317x236.jpg 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2-423x314.jpg 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/EEG-plots-768x571-2-634x471.jpg 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08, .wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08[data-kb-block=\"kb-adv-heading1171_d9a206-08\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08[data-kb-block=\"kb-adv-heading1171_d9a206-08\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08[data-kb-block=\"kb-adv-heading1171_d9a206-08\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08, .wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08[data-kb-block=\"kb-adv-heading1171_d9a206-08\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08, .wp-block-kadence-advancedheading.kt-adv-heading1171_d9a206-08[data-kb-block=\"kb-adv-heading1171_d9a206-08\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_d9a206-08 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_d9a206-08\">Time and frequency plots of the EEG are correlated with voltage to create a power spectrum harmonics. These data are used to extract SWDs from the original EEG signal and subsequently identify absence seizures.<\/p>\n\n\n<style>.kb-row-layout-id1171_e93a09-c3 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_e93a09-c3 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_e93a09-c3 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_e93a09-c3 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_e93a09-c3 > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_e93a09-c3 > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_e93a09-c3 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_0b81f5-78 > .kt-inside-inner-col,.kadence-column1171_0b81f5-78 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_0b81f5-78 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_0b81f5-78 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_0b81f5-78 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_0b81f5-78 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_0b81f5-78{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_0b81f5-78 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_0b81f5-78 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_0b81f5-78\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_e6ced1-ff .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_e6ced1-ff .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_e6ced1-ff .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_e6ced1-ff:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_e6ced1-ff .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_e6ced1-ff .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_e6ced1-ff .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_e6ced1-ff .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_e6ced1-ff .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_e6ced1-ff > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_e6ced1-ff kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_a9f07a-61\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Richard, CD, Tanenbaum, AB, Audit, B, Arneodo, A, Khalil, A, Frankel, WN 2015. SWDreader: A Wavelet-Based Algorithm Using Spectral Phase to Detect and Characterize Spike-Wave Discharges in Three Genetic Mouse Models of Absence Epilepsy, Journal of Neuroscience Methods, 242, 127.&nbsp;<a href=\"https:\/\/doi.org\/10.1016\/j.jneumeth.2014.12.016\">https:\/\/doi.org\/10.1016\/j.jneumeth.2014.12.016<\/a><\/li>\n\n\n\n<li>Richard, Christian 2014. Novel Computational Approaches to Detect and Characterize Absence Seizures in Seizure-Prone Mutant Mouse Strains. PhD Thesis. Functional Genomics. 91爆料.<\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_17d6df-99 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_17d6df-99 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_17d6df-99 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_17d6df-99{background-color:#e5f0f9;}.kb-row-layout-id1171_17d6df-99 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_17d6df-99 > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_17d6df-99 > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_17d6df-99 alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_084e8f-cd > .kt-inside-inner-col,.kadence-column1171_084e8f-cd > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_084e8f-cd > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_084e8f-cd > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_084e8f-cd > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_084e8f-cd > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_084e8f-cd{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_084e8f-cd > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_084e8f-cd > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_084e8f-cd\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_c2633b-6c > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_c2633b-6c > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_c2633b-6c > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_c2633b-6c > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_c2633b-6c > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_c2633b-6c > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_c2633b-6c alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col,.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_c6bf02-b3{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_c6bf02-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_c6bf02-b3\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65, .wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65[data-kb-block=\"kb-adv-heading1171_542bbb-65\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65[data-kb-block=\"kb-adv-heading1171_542bbb-65\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65[data-kb-block=\"kb-adv-heading1171_542bbb-65\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65, .wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65[data-kb-block=\"kb-adv-heading1171_542bbb-65\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65, .wp-block-kadence-advancedheading.kt-adv-heading1171_542bbb-65[data-kb-block=\"kb-adv-heading1171_542bbb-65\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_542bbb-65 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_542bbb-65\">characterization of chromosome territory morphology<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"808\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2.png\" alt=\"\" class=\"wp-image-1036\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2.png 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2-285x300.png 285w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2-105x110.png 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2-317x334.png 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2-423x445.png 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-12.58.50-PM-768x808-2-634x667.png 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_13c3e8-fd{margin-top:-5px;}.kb-row-layout-id1171_13c3e8-fd > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_13c3e8-fd > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_13c3e8-fd > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_13c3e8-fd > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_13c3e8-fd > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_13c3e8-fd > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_13c3e8-fd alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_935041-b3 > .kt-inside-inner-col,.kadence-column1171_935041-b3 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_935041-b3 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_935041-b3 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_935041-b3 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_935041-b3 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_935041-b3{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_935041-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_935041-b3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_935041-b3\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f, .wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f[data-kb-block=\"kb-adv-heading1171_6f255a-0f\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f[data-kb-block=\"kb-adv-heading1171_6f255a-0f\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f[data-kb-block=\"kb-adv-heading1171_6f255a-0f\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f, .wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f[data-kb-block=\"kb-adv-heading1171_6f255a-0f\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f, .wp-block-kadence-advancedheading.kt-adv-heading1171_6f255a-0f[data-kb-block=\"kb-adv-heading1171_6f255a-0f\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_6f255a-0f wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_6f255a-0f\">Examples of wavelet-based segmentation of mouse chromosomes 1 (left) and 12 (right) indicating irregular shape of chromosomes.<\/p>\n\n\n\n<p>While it is known that chromosome territory (CT) size and gene density influence positioning, the relationship between CT shape and positioning is poorly understood. CompuMAINE scientists developed a novel 2D methodology to automatically segment and detect subtle differences in sub-nuclear architecture. It was shown that mouse interphase CTs have highly nonspherical morphology and that CT positioning is nonrandom and favors heterologous CT groupings.<\/p>\n\n\n\n<p>The same technology was used to find CT neighborhoods in mouse lymphocytes. DNA breaks were induced in these cells via radiation. It was determined that inter-CT distances directly relate to translocation partner choice in these cells.<\/p>\n\n\n<style>.kb-row-layout-id1171_06916c-8e > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_06916c-8e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_06916c-8e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_06916c-8e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_06916c-8e > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_06916c-8e > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_06916c-8e alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_2029a2-19 > .kt-inside-inner-col,.kadence-column1171_2029a2-19 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_2029a2-19 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_2029a2-19 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_2029a2-19 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_2029a2-19 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_2029a2-19{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_2029a2-19 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_2029a2-19 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_2029a2-19\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_2283e3-19 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_2283e3-19 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_2283e3-19 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_2283e3-19:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_2283e3-19 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_2283e3-19 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_2283e3-19 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_2283e3-19 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_2283e3-19 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_2283e3-19 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_2283e3-19 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_4a55a3-15\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Khalil, A, Grant, JL, Caddle, LB, Atzema, E, Mills, KD, Arneodo, A 2007. Chromosome territories have a highly non-spherical morphology and non-random positioning. Chromosome Research, 15, 899-916.&nbsp;<a href=\"https:\/\/doi.org\/10.1007\/s10577-007-1172-8\">https:\/\/doi.org\/10.1007\/s10577-007-1172-8<\/a><\/li>\n\n\n\n<li>Caddle, LB, Grant, JL, van Hase, J, Denegre, J, Shirley, BJ, Bewersdorf, J, Cremer, C, Arneodo, A, Khalil, A, &amp; Mills, KD 2007 Heterologous chromosome territory neighborhoods promote translocation susceptibility in primary lymphocytes. Chromosome Research, 15, 1061-1073.&nbsp;<a href=\"https:\/\/doi.org\/10.1007\/s10577-007-1181-7\">https:\/\/doi.org\/10.1007\/s10577-007-1181-7<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_0af5b1-59 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_0af5b1-59 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_0af5b1-59 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_0af5b1-59{background-image:linear-gradient(135deg,rgb(8,46,88) 0%,rgb(65,118,161) 99%);}.kb-row-layout-id1171_0af5b1-59 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_0af5b1-59 > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_0af5b1-59 > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_0af5b1-59 alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_2dc513-fa > .kt-inside-inner-col,.kadence-column1171_2dc513-fa > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_2dc513-fa > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_2dc513-fa > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_2dc513-fa > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_2dc513-fa > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_2dc513-fa{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_2dc513-fa > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_2dc513-fa > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_2dc513-fa\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_45cf2d-1e > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_45cf2d-1e > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_45cf2d-1e > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_45cf2d-1e > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_45cf2d-1e > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_45cf2d-1e > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_45cf2d-1e alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_a88326-6e > .kt-inside-inner-col,.kadence-column1171_a88326-6e > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_a88326-6e > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_a88326-6e > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_a88326-6e > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_a88326-6e > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_a88326-6e{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_a88326-6e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_a88326-6e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_a88326-6e\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f, .wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f[data-kb-block=\"kb-adv-heading1171_9b643e-9f\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f[data-kb-block=\"kb-adv-heading1171_9b643e-9f\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f[data-kb-block=\"kb-adv-heading1171_9b643e-9f\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f, .wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f[data-kb-block=\"kb-adv-heading1171_9b643e-9f\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f, .wp-block-kadence-advancedheading.kt-adv-heading1171_9b643e-9f[data-kb-block=\"kb-adv-heading1171_9b643e-9f\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_9b643e-9f wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_9b643e-9f\">structure and organization of chromosomes in huntington&#8217;s disease<\/h2>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_7991b2-f2{margin-top:-5px;}.kb-row-layout-id1171_7991b2-f2 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_7991b2-f2 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_7991b2-f2 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_7991b2-f2 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_7991b2-f2 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_7991b2-f2 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_7991b2-f2 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_087b66-5a > .kt-inside-inner-col,.kadence-column1171_087b66-5a > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_087b66-5a > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_087b66-5a > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_087b66-5a > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_087b66-5a > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_087b66-5a{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_087b66-5a > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_087b66-5a > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_087b66-5a\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4, .wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4[data-kb-block=\"kb-adv-heading1171_161d90-c4\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4[data-kb-block=\"kb-adv-heading1171_161d90-c4\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_161d90-c4[data-kb-block=\"kb-adv-heading1171_161d90-c4\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading1171_161d90-c4 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_161d90-c4\">While the genetic basis of Huntington\u2019s disease (HD) was discovered in 1993, the exact mechanism of the disease\u2019s progression is still unknown. Cells from individuals with early HD, individuals with moderate HD, and a control group were stained using florescence markers and imaged. These images were then analyzed and segmented using a combination of machine learning and specialized thresholding algorithms. Measurable changes in the structure and organization of chromosomes were identified. These changes in chromosome structure and organization could potentially provide a new avenue for diagnosis and treatment.<\/p>\n\n\n<style>.kb-image1171_66871e-f7 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image1171_66871e-f7 size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"765\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2.jpg\" alt=\"\" class=\"kb-img wp-image-1049\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2.jpg 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-300x300.jpg 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-150x150.jpg 150w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-105x105.jpg 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-317x316.jpg 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-423x421.jpg 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-634x632.jpg 634w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Nuclei-768x765-2-32x32.jpg 32w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2[data-kb-block=\"kb-adv-heading1171_b6c333-d2\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2[data-kb-block=\"kb-adv-heading1171_b6c333-d2\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2[data-kb-block=\"kb-adv-heading1171_b6c333-d2\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2[data-kb-block=\"kb-adv-heading1171_b6c333-d2\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2, .wp-block-kadence-advancedheading.kt-adv-heading1171_b6c333-d2[data-kb-block=\"kb-adv-heading1171_b6c333-d2\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_b6c333-d2 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_b6c333-d2\">A machine-learning algorithm detects and segments nuclei in a Huntington\u2019s disease sample.<\/p>\n\n\n<style>.kb-row-layout-id1171_1535f7-a8 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_1535f7-a8 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_1535f7-a8 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_1535f7-a8 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_1535f7-a8 > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_1535f7-a8 > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_1535f7-a8 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_79494b-2e > .kt-inside-inner-col,.kadence-column1171_79494b-2e > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_79494b-2e > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_79494b-2e > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_79494b-2e > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_79494b-2e > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_79494b-2e{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_79494b-2e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_79494b-2e > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_79494b-2e\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_12f70d-03 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_12f70d-03 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_12f70d-03 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_12f70d-03:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_12f70d-03 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_12f70d-03 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_12f70d-03 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_12f70d-03 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_12f70d-03 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_12f70d-03 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_12f70d-03 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_cb9724-fa\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Toner, Brian 2015. The Geometric Properties of Cells Exhibiting Huntington\u2019s Disease. MA Thesis. Mathematics. 91爆料.&nbsp;<a href=\"https:\/\/digitalcommons.library.umaine.edu\/etd\/2304\/\">https:\/\/digitalcommons.library.umaine.edu\/etd\/2304\/<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_9387f9-75 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_9387f9-75 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_9387f9-75 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_9387f9-75{background-color:#e5f0f9;}.kb-row-layout-id1171_9387f9-75 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_9387f9-75 > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_9387f9-75 > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_9387f9-75 alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col,.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_0d7d72-c2{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_0d7d72-c2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_0d7d72-c2\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_3f8e66-9c > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_3f8e66-9c > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_3f8e66-9c > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_3f8e66-9c > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_3f8e66-9c > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_3f8e66-9c > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_3f8e66-9c alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_0f9434-8f > .kt-inside-inner-col,.kadence-column1171_0f9434-8f > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_0f9434-8f > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_0f9434-8f > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_0f9434-8f > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_0f9434-8f > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_0f9434-8f{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_0f9434-8f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_0f9434-8f > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_0f9434-8f\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34, .wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34[data-kb-block=\"kb-adv-heading1171_c365af-34\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34[data-kb-block=\"kb-adv-heading1171_c365af-34\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34[data-kb-block=\"kb-adv-heading1171_c365af-34\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34, .wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34[data-kb-block=\"kb-adv-heading1171_c365af-34\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34, .wp-block-kadence-advancedheading.kt-adv-heading1171_c365af-34[data-kb-block=\"kb-adv-heading1171_c365af-34\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_c365af-34 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_c365af-34\">detection and quantification of nuclear architecture in <em>c. elegans<\/em><\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1560\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3.jpg\" alt=\"\" class=\"wp-image-1058\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3.jpg 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-148x300.jpg 148w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-504x1024.jpg 504w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-756x1536.jpg 756w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-69x140.jpg 69w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-317x644.jpg 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-423x859.jpg 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/individual-xy-cross-sections-768x1560-3-634x1288.jpg 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_c32a3d-6f{margin-top:-5px;}.kb-row-layout-id1171_c32a3d-6f > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_c32a3d-6f > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_c32a3d-6f > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_c32a3d-6f > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_c32a3d-6f > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_c32a3d-6f > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_c32a3d-6f alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_b69a09-1b > .kt-inside-inner-col,.kadence-column1171_b69a09-1b > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_b69a09-1b > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_b69a09-1b > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_b69a09-1b > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_b69a09-1b > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_b69a09-1b{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_b69a09-1b > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_b69a09-1b > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_b69a09-1b\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d, .wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d[data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d[data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d[data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d, .wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d[data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d, .wp-block-kadence-advancedheading.kt-adv-heading1171_f4b6ad-6d[data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_f4b6ad-6d wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_f4b6ad-6d\">The top image shows the individual xy cross-sections of embryonic nuclei. The middle image shows the wavelet-segmented cross-sections stacked in z-plane. The bottom image shows 3D reconstruction of embryonic nuclei.<\/p>\n\n\n\n<p>Specific nuclear domains are nonrandomly positioned within nuclear space, and this preferential positioning plays an important role in genome activity and stability. CompuMAINE scientists characterized intranuclear positioning of&nbsp;<em>Caenorhabditis elegans<\/em>&nbsp;HPL-2, which is a marker for heterochromatin domains in developing embryos.<\/p>\n\n\n\n<p>CompuMAINE used a wavelet-based automatic segmentation method to isolate nuclei from images of&nbsp;<em>C. elegans<\/em>&nbsp;embryos. These nuclei were then analyzed for fluorescence intensity, which indicated positions of HPL-2.<\/p>\n\n\n<style>.kb-row-layout-id1171_435c3d-bf > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_435c3d-bf > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_435c3d-bf > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_435c3d-bf > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_435c3d-bf > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_435c3d-bf > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_435c3d-bf alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_a425ae-a5 > .kt-inside-inner-col,.kadence-column1171_a425ae-a5 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_a425ae-a5 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_a425ae-a5 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_a425ae-a5 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_a425ae-a5 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_a425ae-a5{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_a425ae-a5 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_a425ae-a5 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_a425ae-a5\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_6a8e66-43 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_6a8e66-43 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_6a8e66-43 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_6a8e66-43:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_6a8e66-43 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_6a8e66-43 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_6a8e66-43 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_6a8e66-43 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_6a8e66-43 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_6a8e66-43 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_6a8e66-43 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_ed498f-59\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Grant, J, Verrill, C, Coustham, V, Arneodo, A, Paladino, F, Monier, K, Khalil, A 2010. Perinuclear distribution of heterochromatin in developing C. elegans embryos, Chromosome Research, 18, 873-885.&nbsp;<a href=\"https:\/\/doi.org\/10.1007\/s10577-010-9175-2\">https:\/\/doi.org\/10.1007\/s10577-010-9175-2<\/a><\/li>\n\n\n\n<li>Grant, Jeremy 2008. Wavelet-Based Segmentation of Fluorescence Microscopy Images in Two and Three Dimensions. MA Thesis. Mathematics. 91爆料.&nbsp;<a href=\"https:\/\/digitalcommons.library.umaine.edu\/etd\/1022\/\">https:\/\/digitalcommons.library.umaine.edu\/etd\/1022\/<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_f33943-23 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_f33943-23 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_f33943-23 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_f33943-23{background-image:linear-gradient(135deg,rgb(8,46,88) 0%,rgb(65,118,161) 99%);}.kb-row-layout-id1171_f33943-23 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_f33943-23 > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_f33943-23 > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_f33943-23 alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_e8e472-08 > .kt-inside-inner-col,.kadence-column1171_e8e472-08 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_e8e472-08 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_e8e472-08 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_e8e472-08 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_e8e472-08 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_e8e472-08{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_e8e472-08 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_e8e472-08 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_e8e472-08\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_d43369-d7 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_d43369-d7 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_d43369-d7 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_d43369-d7 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_d43369-d7 > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_d43369-d7 > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_d43369-d7 alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_db1102-e4 > .kt-inside-inner-col,.kadence-column1171_db1102-e4 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_db1102-e4 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_db1102-e4 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_db1102-e4 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_db1102-e4 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_db1102-e4{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_db1102-e4 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_db1102-e4 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_db1102-e4\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf, .wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf[data-kb-block=\"kb-adv-heading1171_be6a6e-bf\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf[data-kb-block=\"kb-adv-heading1171_be6a6e-bf\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf[data-kb-block=\"kb-adv-heading1171_be6a6e-bf\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf, .wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf[data-kb-block=\"kb-adv-heading1171_be6a6e-bf\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf, .wp-block-kadence-advancedheading.kt-adv-heading1171_be6a6e-bf[data-kb-block=\"kb-adv-heading1171_be6a6e-bf\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_be6a6e-bf wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_be6a6e-bf\">Characterization of chromosome territory morphology and intermingling<\/h2>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_984b83-a4{margin-top:-5px;}.kb-row-layout-id1171_984b83-a4 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_984b83-a4 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_984b83-a4 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_984b83-a4 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_984b83-a4 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_984b83-a4 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_984b83-a4 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col,.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_e47ea3-f3{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_e47ea3-f3 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_e47ea3-f3\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14, .wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14[data-kb-block=\"kb-adv-heading1171_493036-14\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14[data-kb-block=\"kb-adv-heading1171_493036-14\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_493036-14[data-kb-block=\"kb-adv-heading1171_493036-14\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<p class=\"kt-adv-heading1171_493036-14 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_493036-14\">There is currently a large gap in the tumor cytological analyses where observer bias deeply influences interpretation of signals and changes in cell intra-and extra-nuclear morphology, positioning, and overall organization. CompuMAINE developed a novel 3D methodology that automatically segments and detects subtle differences in sub-nuclear architecture. This method potentially can be used to score images of nuclei for pathological changes.<\/p>\n\n\n<style>.kb-image1171_bfd5c0-47 .kb-image-has-overlay:after{opacity:0.3;}<\/style>\n<figure class=\"wp-block-kadence-image kb-image1171_bfd5c0-47 size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"386\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2.png\" alt=\"\" class=\"kb-img wp-image-1066\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2.png 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2-300x151.png 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2-105x53.png 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2-317x159.png 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2-423x213.png 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2025\/06\/Screen-Shot-2019-02-11-at-1.41.21-PM-768x386-2-634x319.png 634w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,768px\" \/><\/figure>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35, .wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35[data-kb-block=\"kb-adv-heading1171_16cb9f-35\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35[data-kb-block=\"kb-adv-heading1171_16cb9f-35\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35[data-kb-block=\"kb-adv-heading1171_16cb9f-35\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35, .wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35[data-kb-block=\"kb-adv-heading1171_16cb9f-35\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35, .wp-block-kadence-advancedheading.kt-adv-heading1171_16cb9f-35[data-kb-block=\"kb-adv-heading1171_16cb9f-35\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_16cb9f-35 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_16cb9f-35\">The left depicts a 3D representation of two chromosome territories. The right contains a 3D representation of overlapping chromosome territories. The yellow area is the site of chromosome intermingling.<\/p>\n\n\n<style>.kb-row-layout-id1171_adb947-76 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_adb947-76 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_adb947-76 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_adb947-76 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_adb947-76 > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_adb947-76 > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_adb947-76 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_ed458b-66 > .kt-inside-inner-col,.kadence-column1171_ed458b-66 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_ed458b-66 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_ed458b-66 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_ed458b-66 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_ed458b-66 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_ed458b-66{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_ed458b-66 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_ed458b-66 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_ed458b-66\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_c251fa-f9 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_c251fa-f9 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_c251fa-f9 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_c251fa-f9:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_c251fa-f9 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_c251fa-f9 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_c251fa-f9 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_c251fa-f9 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_c251fa-f9 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_c251fa-f9 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_c251fa-f9 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_89b514-96\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Khalil, A, Grant, JL, Caddle, LB, Atzema, E, Mills, KD, Arneodo, A 2007. Chromosome territories have a highly non-spherical morphology and non-random positioning. Chromosome Research, 15, 899-916.&nbsp;<a href=\"http:\/\/doi.org\/10.1007\/s10577-007-1172-8\">http:\/\/doi.org\/10.1007\/s10577-007-1172-8<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.kb-row-layout-id1171_38097e-ae > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_38097e-ae > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_38097e-ae > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);max-width:1100px;margin-left:auto;margin-right:auto;padding-top:75px;padding-bottom:75px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_38097e-ae{background-color:#e5f0f9;}.kb-row-layout-id1171_38097e-ae > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_38097e-ae > .kt-row-column-wrap{padding-right:50px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_38097e-ae > .kt-row-column-wrap{padding-top:50px;padding-right:25px;padding-bottom:50px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_38097e-ae alignfull kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_e61c2b-bf > .kt-inside-inner-col,.kadence-column1171_e61c2b-bf > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_e61c2b-bf > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_e61c2b-bf > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_e61c2b-bf > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_e61c2b-bf > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_e61c2b-bf{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_e61c2b-bf > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_e61c2b-bf > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_e61c2b-bf\"><div class=\"kt-inside-inner-col\"><style>.kb-row-layout-id1171_bb5e19-7f > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_bb5e19-7f > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_bb5e19-7f > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:60px;padding-right:170px;padding-bottom:60px;padding-left:170px;grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_bb5e19-7f > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_bb5e19-7f > .kt-row-column-wrap{padding-top:35px;padding-right:35px;padding-bottom:45px;padding-left:35px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_bb5e19-7f > .kt-row-column-wrap{padding-bottom:35px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_bb5e19-7f alignnone has-white-background-color kt-row-has-bg wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_7200ca-36 > .kt-inside-inner-col,.kadence-column1171_7200ca-36 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_7200ca-36 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_7200ca-36 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_7200ca-36 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_7200ca-36 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_7200ca-36{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_7200ca-36 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_7200ca-36 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_7200ca-36\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0[data-kb-block=\"kb-adv-heading1171_d7a90d-b0\"]{text-align:center;font-size:32px;font-weight:900;font-style:normal;font-family:stratum-1-web;text-transform:uppercase;color:#003263;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0[data-kb-block=\"kb-adv-heading1171_d7a90d-b0\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0[data-kb-block=\"kb-adv-heading1171_d7a90d-b0\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0[data-kb-block=\"kb-adv-heading1171_d7a90d-b0\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0, .wp-block-kadence-advancedheading.kt-adv-heading1171_d7a90d-b0[data-kb-block=\"kb-adv-heading1171_d7a90d-b0\"]{text-align:center!important;}}<\/style>\n<h2 class=\"kt-adv-heading1171_d7a90d-b0 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_d7a90d-b0\">fractal properties of pascal&#8217;s triangle modulo primes<\/h2>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"3125\" height=\"871\" src=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas.jpg\" alt=\"Photo of Students at the Board with Instructor\" class=\"wp-image-65\" srcset=\"https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas.jpg 3125w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-300x84.jpg 300w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-768x214.jpg 768w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-1024x285.jpg 1024w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-105x29.jpg 105w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-600x168.jpg 600w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-317x88.jpg 317w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-423x118.jpg 423w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-634x177.jpg 634w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-846x236.jpg 846w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-951x265.jpg 951w, https:\/\/umaine.edu\/compumaine\/wp-content\/uploads\/sites\/495\/2019\/02\/numberical-ideas-1268x353.jpg 1268w\" sizes=\"auto, (max-width: 320px) 85vw, (max-width: 768px) 67vw, (max-width: 1024px) 62vw,3125px\" \/><\/figure>\n\n\n<style>.kb-row-layout-wrap.wp-block-kadence-rowlayout.kb-row-layout-id1171_95d0da-84{margin-top:-5px;}.kb-row-layout-id1171_95d0da-84 > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_95d0da-84 > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_95d0da-84 > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_95d0da-84 > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_95d0da-84 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_95d0da-84 > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_95d0da-84 alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_ea1351-a2 > .kt-inside-inner-col,.kadence-column1171_ea1351-a2 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_ea1351-a2 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_ea1351-a2 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_ea1351-a2 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_ea1351-a2 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_ea1351-a2{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_ea1351-a2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_ea1351-a2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_ea1351-a2\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61, .wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61[data-kb-block=\"kb-adv-heading1171_c2fd4a-61\"]{margin-top:0px;font-size:18px;font-weight:400;font-style:normal;font-family:forma-djr-micro;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61[data-kb-block=\"kb-adv-heading1171_c2fd4a-61\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61[data-kb-block=\"kb-adv-heading1171_c2fd4a-61\"] img.kb-inline-image{width:150px;vertical-align:baseline;}@media all and (max-width: 1024px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61, .wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61[data-kb-block=\"kb-adv-heading1171_c2fd4a-61\"]{text-align:left!important;}}@media all and (max-width: 767px){.wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61, .wp-block-kadence-advancedheading.kt-adv-heading1171_c2fd4a-61[data-kb-block=\"kb-adv-heading1171_c2fd4a-61\"]{text-align:center!important;}}<\/style>\n<p class=\"kt-adv-heading1171_c2fd4a-61 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading1171_c2fd4a-61\">Developing theoretical ideas based on numerical investigations of the fractal properties of Pascal&#8217;s Triangle.<\/p>\n\n\n\n<p>Pascal\u2019s triangle modulo a prime number yields an infinite array of numbers that display interesting fractal properties. One way to quantitatively describe these fractal patterns is via the so-called box-counting dimension. Two CompuMAINE students (Matt Potter and Elliot Ossana) and collaborators Rob Niemeyer and David Bradley have teamed up with Dr. Khalil to work on this project. A paper is currently under peer review at the journal Fractals.<\/p>\n\n\n<style>.kb-row-layout-id1171_dac9bc-5f > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id1171_dac9bc-5f > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id1171_dac9bc-5f > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 1fr);}.kb-row-layout-id1171_dac9bc-5f > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id1171_dac9bc-5f > .kt-row-column-wrap{padding-top:0px;padding-right:50px;padding-bottom:0px;padding-left:50px;grid-template-columns:minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id1171_dac9bc-5f > .kt-row-column-wrap{padding-right:25px;padding-left:25px;grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id1171_dac9bc-5f alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-1-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column1171_89412c-24 > .kt-inside-inner-col,.kadence-column1171_89412c-24 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column1171_89412c-24 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column1171_89412c-24 > .kt-inside-inner-col{flex-direction:column;}.kadence-column1171_89412c-24 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column1171_89412c-24 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column1171_89412c-24{position:relative;}@media all and (max-width: 1024px){.kadence-column1171_89412c-24 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column1171_89412c-24 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column1171_89412c-24\"><div class=\"kt-inside-inner-col\"><style>.kt-accordion-id1171_471e8c-83 .kt-accordion-inner-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:2px;}.kt-accordion-id1171_471e8c-83 .kt-accordion-panel-inner{padding-top:35px;padding-right:35px;padding-bottom:35px;padding-left:35px;}.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;background:#082e58;font-size:20px;line-height:24px;font-family:stratum-1-web;font-weight:900;text-transform:uppercase;color:#fff;padding-top:25px;padding-right:25px;padding-bottom:25px;padding-left:25px;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83 .kt-blocks-accordion-header:focus-visible{color:#fff;background:#082e58;border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion--visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle ) .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger, body:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:hover .kt-blocks-accordion-icon-trigger:before, body:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:after, body:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible .kt-blocks-accordion-icon-trigger:before{background:#082e58;}.kt-accordion-id1171_471e8c-83 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{color:#fff;background:#082e58;border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basiccircle ):not( .kt-accodion-icon-style-xclosecircle ):not( .kt-accodion-icon-style-arrowcircle )  > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger{background:#fff;}.kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:after, .kt-accordion-id1171_471e8c-83:not( .kt-accodion-icon-style-basic ):not( .kt-accodion-icon-style-xclose ):not( .kt-accodion-icon-style-arrow ) .kt-blocks-accordion-header.kt-accordion-panel-active .kt-blocks-accordion-icon-trigger:before{background:#082e58;}@media all and (max-width: 1024px){.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}}@media all and (max-width: 1024px){.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}}@media all and (max-width: 1024px){.kt-accordion-id1171_471e8c-83 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}@media all and (max-width: 767px){.kt-accordion-id1171_471e8c-83 .kt-accordion-inner-wrap{display:block;}.kt-accordion-id1171_471e8c-83 .kt-accordion-inner-wrap .kt-accordion-pane:not(:first-child){margin-top:2px;}.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #003263;}.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header:hover, \n\t\t\t\tbody:not(.hide-focus-outline) .kt-accordion-id1171_471e8c-83 .kt-blocks-accordion-header:focus-visible{border-top:1px solid #d6d6d6;border-right:1px solid #d6d6d6;border-bottom:1px solid #d6d6d6;border-left:10px solid #79bde8;}.kt-accordion-id1171_471e8c-83 .kt-accordion-header-wrap .kt-blocks-accordion-header:focus-visible,\n\t\t\t\t.kt-accordion-id1171_471e8c-83 > .kt-accordion-inner-wrap > .wp-block-kadence-pane > .kt-accordion-header-wrap > .kt-blocks-accordion-header.kt-accordion-panel-active{border-top:1px solid #eee;border-right:1px solid #eee;border-bottom:1px solid #eee;border-left:10px solid #003263;}}<\/style>\n<div class=\"wp-block-kadence-accordion alignnone um-UMBlueAccordion\"><div class=\"kt-accordion-wrap kt-accordion-id1171_471e8c-83 kt-accordion-has-5-panes kt-active-pane-0 kt-accordion-block kt-pane-header-alignment-left kt-accodion-icon-style-basiccircle kt-accodion-icon-side-right\" style=\"max-width:none\"><div class=\"kt-accordion-inner-wrap\" data-allow-multiple-open=\"false\" data-start-open=\"none\">\n<div class=\"wp-block-kadence-pane kt-accordion-pane kt-accordion-pane-1 kt-pane1171_751088-1c\"><div class=\"kt-accordion-header-wrap\"><button class=\"kt-blocks-accordion-header kt-acccordion-button-label-show\" type=\"button\"><span class=\"kt-blocks-accordion-title-wrap\"><span class=\"kt-blocks-accordion-title\">selected references<\/span><\/span><span class=\"kt-blocks-accordion-icon-trigger\"><\/span><\/button><\/div><div class=\"kt-accordion-panel kt-accordion-panel-hidden\"><div class=\"kt-accordion-panel-inner\">\n<ol class=\"wp-block-list\">\n<li>Bradley, DM, D\u2019Alessio, D, Khalil, A, Niemeyer, RG, Ossanna, E, Tanenbaum, A, Toner, B 2019,&nbsp;<em>On the relative frequency of residue classes in Pascal\u2019s Triangle modulo a prime<\/em>.&nbsp;Fractals, In press.&nbsp;<a href=\"https:\/\/doi.org\/10.1142\/S0218348X19500981\">https:\/\/doi.org\/10.1142\/S0218348X19500981<\/a><\/li>\n\n\n\n<li>Bradley, DM, Khalil, A, Niemeyer, RG, Ossanna, E 2018&nbsp;<em>The Box-Counting Dimension of Pascal\u2019s Triangle r mod p<\/em>.&nbsp;Fractals, 26, 05, 1850071.&nbsp;<a href=\"https:\/\/doi.org\/10.1142\/S0218348X18500718\">https:\/\/doi.org\/10.1142\/S0218348X18500718<\/a><\/li>\n\n\n\n<li>Ossanna, Elliot 2015.&nbsp;<em>Fractal Dimension of Residues Sets Within Pascal\u2019s Triangle Under Square-Free Moduli<\/em>.&nbsp;Honors Thesis. Mathematics. 91爆料.&nbsp;<a href=\"http:\/\/www.math.umaine.edu\/~khalil\/courses\/MAT400\/Thesis%20FInal.pdf\">http:\/\/www.math.umaine.edu\/~khalil\/courses\/MAT400\/Thesis%20FInal.pdf<\/a><\/li>\n\n\n\n<li>Potter, Matthew 2010.&nbsp;<em>Prime Modulo and Pascal\u2019s Triangle As Seen With Fractal Geometry<\/em>.&nbsp;MA Thesis. Mathematics. 91爆料.&nbsp;<a href=\"https:\/\/digitalcommons.library.umaine.edu\/etd\/1011\/\">https:\/\/digitalcommons.library.umaine.edu\/etd\/1011\/<\/a><\/li>\n<\/ol>\n<\/div><\/div><\/div>\n<\/div><\/div><\/div>\n<\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div><\/div><\/div>\n\n<\/div><\/div>\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-1171_3d1f48-fe .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-1171_3d1f48-fe .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}@media all and (max-width: 767px){.wp-block-kadence-spacer.kt-block-spacer-1171_3d1f48-fe .kt-block-spacer{height:35px!important;}}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-1171_3d1f48-fe\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>projects at compumaine microenvironment disruption in tumorous breasts We successfully demonstrated preliminary evidence that tissue disruption and loss of homeostasis in breast tissue microenvironment and breast bilateral asymmetry can be quantitatively and objectively assessed from mammography via a localized, wavelet-based analysis of the whole breast. The WTMM method was used to quantify density fluctuations from [&hellip;]<\/p>\n","protected":false},"author":2592,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-1171","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Projects - CompuMAINE - 91爆料<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/umaine.edu\/compumaine\/projects-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Projects - CompuMAINE - 91爆料\" \/>\n<meta property=\"og:description\" content=\"projects at compumaine microenvironment disruption in tumorous breasts We successfully demonstrated preliminary evidence that tissue disruption and loss of homeostasis in breast tissue microenvironment and breast bilateral asymmetry can be quantitatively and objectively assessed from mammography via a localized, wavelet-based analysis of the whole breast. 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